PRX Plus is a next-generation skin revitalization treatment that combines collagen stimulation with brightening benefits to smooth wrinkles and fade pigmentation without downtime.

Advanced Skin Revitalization with Brightening Benefits
At Pretty with Poulos, we’re proud to offer PRX Plus, a next-generation topical biostimulator designed to improve firmness, reduce deep wrinkles, and target unwanted pigmentation. Building on the success of PRX Derm Perfexion, PRX Plus revitalizes the skin from the inside out, without peeling, needles, or downtime.
What Is PRX Plus?
PRX Plus is a noninvasive, professional-grade treatment for uneven skin tone that combines the rejuvenating power of collagen stimulation with a brightening effect. Its patented blend of trichloroacetic acid (TCA), hydrogen peroxide, and kojic acid penetrates below the surface to trigger cellular renewal, leaving the outer skin layer intact.
The result? Refreshed, firmer, and even-toned skin without the downtime or peeling often associated with chemical peels or lasers.
Who Is a Candidate?
PRX Plus is safe for all skin types and tones. You may be an ideal candidate if you struggle with concerns like deep wrinkles, pigmentation, loss of elasticity, or dull and uneven skin. During your private consultation, Dr. Poulos and her team will evaluate your skin, review your goals, and recommend whether PRX Plus or another treatment, such as PRX Derm Perfexion or microneedling, is best for you.
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Contact UsPRX vs. PRX Plus: Which Is Right for You?
| PRX Derm Perfexion (PRX) | PRX Plus |
| Stimulates collagen for firmer, smoother skin | Stimulates collagen and brightens uneven pigmentation |
| Improves fine lines, texture, and pore size | Improves fine lines and deeper wrinkles |
| Creates an overall radiant, refreshed look | Provides rejuvenation plus corrective results for pigmentation and advanced aging |
| Best for patients seeking general skin rejuvenation | Best for patients with pigmentation concerns or more significant wrinkles |
If you’re unsure which treatment is right, Dr. Poulos will recommend the ideal option based on your skin’s needs and goals.
Results and Recovery
One key advantage of PRX Plus is that it requires no downtime. Your skin may appear brighter, plumper, and refreshed immediately after treatment. Some mild redness or light flaking can occur, but this resolves quickly with proper skincare.
A full series of treatments is recommended for the best long-term improvements in firmness, texture, and pigmentation. Most patients see optimal results with about five sessions, spaced two weeks apart.
Why Choose Dr. Poulos for PRX Plus?
At Pretty with Poulos, every treatment is guided by Dr. Cynthia Poulos’ decades of expertise, artistic eye, and commitment to patient safety. Known throughout Worcester County and beyond, Dr. Poulos provides a boutique-level medspa experience where every patient receives individualized care in a safe, comfortable environment.
By combining her medical expertise with the latest advancements in non-invasive treatments, Dr. Poulos ensures you achieve natural-looking, lasting results—so you can look refreshed, radiant, and confident.
Schedule Your Consultation
Ready to experience smoother, brighter, firmer skin without downtime? Discover what PRX Plus in Northborough can do for you. Contact Pretty With Poulos today to schedule your private consultation.
FAQs
How is PRX Plus different from PRX Derm Perfexion?
PRX Plus offers all the collagen-stimulating benefits of PRX Derm Perfexion but adds enhanced brightening and deeper wrinkle reduction. It’s designed for patients who want both rejuvenation and correction of pigmentation or more advanced lines.
Is PRX Plus safe for all skin types?
Yes. PRX Plus is suitable for all skin tones and most skin types. However, it may not be recommended for patients with irritated skin, active skin infections, or certain medical conditions. A consultation with Dr. Poulos will confirm your candidacy.
How many treatments will I need?
You will see visible results after your first session, but a series of about five treatments spaced two weeks apart is recommended for long-lasting improvement.
Is there any downtime?
No. You can return to your daily activities immediately after treatment. Some patients may experience mild redness or light flaking, which resolves quickly.
Can I combine PRX Plus with other treatments?
Yes. PRX Plus can be safely paired with treatments such as microneedling or injectables for enhanced results. Dr. Poulos will design a customized plan to meet your goals.
When will I see results?
Right after treatment, your skin will look brighter and refreshed. As collagen remodeling continues over the following weeks and months, you’ll notice improvements in firmness, tone, and pigmentation.

